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Table 2 Allelic variants in the 5' flanking regions of ENaC subunits in Dahl S, R, Wistar, and Brown Norway rats.

From: Sequence analysis of coding and 3' and 5' flanking regions of the epithelial sodium channel α, β, and γ genes in Dahl S versus R rats

Subunit

Nucleotide Position

Dahl S and R

Wistar

Brown Norway

ENaC α

-705

TT

TT

CC, CT, TT

 

-1050

AA

AA

GG, GA, AA

 

-1247

TT

TT

AA, AT, TT

 

-1788

Deletion of 5GCTs

Deletion of 5GCTs

 

ENaC β

-34381

AA

GG, GA, AA

GG, GA, AA

 

-34648

AA

GG, GA, AA

GG

ENaC γ

-1118

Insertion of CCCCCA

  
 

-1588

CC

AA, AC, CC

AA

 

-2054

TT

TT, CT, CC

CC, CT, TT

 

-2386

GG

AA*

AA

 

-2525

AA

GG, GA, AA

GG

 

-2561

GG

AA, AG, GG

AA

 

-3313

CC

CC

TT

  1. Numbering starts at the A nucleotide of the primary initiation codon [15].
  2. * GG genotype was previously reported [7].