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Table 1 Proportion of trait variance (standard error) attributable to the additive and dominance effect of genes and the residual variance attributed to the environment among the OOA, Lancaster County PA

From: Homozygosity by descent mapping of blood pressure in the Old Order Amish: evidence for sex specific genetic architecture

   

Proportion of Variance

Trait

Number

Mean (SD) mmHg

Additive

Dominance

Environmental

With those on medication removed

SBP

585

121.3 (15.9)

0.14 (0.12)

0.32 (0.28)

0.54 (0.21)

DBP

585

78.3 (9.2)

0.17 (0.12)

0.25 (0.25)

0.59 (0.18)

Adding a constant to those on medication

SBP

616

123.6 (19.1)

0.04 (0.13)

0.96 (0.13)

0.00

DBP

616

79.0 (10.1)

0.16 (0.11)

0.46 (0.27)

0.38 (0.21)

Ignoring medication use

SBP

616

123.1 (18.1)

0.08 (0.12)

0.76 (0.33)

0.17 (0.25)

DBP

616

78.8 (9.8)

0.17 (0.11)

0.37 (0.26)

0.46 (0.20)