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Table 1 Number of transmission errors occurring within and outside regions of extended homozygosity > 1 Mb compared with chance expectation

From: Extended homozygosity is not usually due to cytogenetic abnormality

Subject Observed number of "lost allele" errors related to regions of homozygosity of > 1 Mb Proportion of markers falling within regions Expected number of errors to be related to regions of homozygosity of > 1 Mb
  Within regions Outside regions   Within regions Outside regions
1 0 239 0.0096 2.3 236.7
2 0 245 0.0094 2.3 242.7
3 3 274 0.0083 2.3 274.7
4 1 261 0.0092 2.4 259.6
5 1 244 0.0073 1.8 243.2
6 1 605 0.0068 4.1 601.9
7 0 597 0.0020 1.2 595.8
8 0 488 0.0025 1.2 486.8
9 0 602 0.0017 1.0 601.0
10 0 556 0.0029 1.6 554.4
Total* 6 4111 0.0049 20.2 4096.8
  1. *Chi-squared = 10.0, 1 df, p = 0.0015.