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Table 1 Summary statistics for 15 half-sib families used to evaluate GDF8

From: Evidence for multiple alleles effecting muscling and fatness at the Ovine GDF8 locus

   

GDF8 Haplotype3

Hap

Sire

Breed 1

Progeny 2

1

2

3

4

5

ID 4

S1

P(24)

90

186

C

A

G

139

1

   

204

C

A

G

135

2

S2

P(11)T(13)

95

192

C

A

G

149

3

   

218

C

A

A

141

4

S3

P(15)

87

186

A

A

G

141

5

   

216

C

A

G

151

6

S4

P(23)

80

222

C

A

G

149

7

   

192

C

A

G

135

8

S5

P(28)

72

204

C

A

G

135

2

   

188

A

A

G

149

9

S6

P(19)

92

186

A

A

G

141

5

   

204

C

A

G

135

2

S7

P(18)

85

186

C

A

G

139

1

   

192

C

A

G

149

3

S8

P(28)

43

216

C

A

G

151

6

   

204

C

A

G

135

2

S9

W(28)

95

184

C

A

G

139

10

   

188

A

A

G

151

11

S10

P(1)S(3)W(18)

53

218

C

A

G

135

12

   

186

A

C

G

137

13

S11

P(1)S(5)T(3)W(21)

79

218

C

A

A

141

4

   

218

C

A

G

137

14

S12

S(2)W(28)

81

216

A

C

G

139

15

   

216

C

A

G

137

16

S13

P(1)S(9)W(10)

62

192

C

A

G

135

8

   

214

A

A

G

149

17

S14

S(9)T(9)

95

218

C

A

A

141

4

   

186

C

A

G

137

18

S15

P(19)

82

212

C

A

G

149

19

   

216

A

C

G

143

20

  1. 1 Male and female ancestors of each sire present within five generation pedigrees are given as P (Poll Dorset), S (Suffolk), T (Texel) or W (White Suffolk). The number of ancestors of each breed type is given in brackets.
  2. 2 The number of half-sib progeny used for association analysis.
  3. 3GDF8 haplotypes for each sire comprise alleles at five markers encoded as follows: 1 (BM81124), 2 (g-41C>A), 3 (g+4036A>C), 4 (g+6723G>A) and 5 (BULGE20). Alleles are given in base pairs for the two microsatellite markers and nucleotides for the three SNP. Alleles which occur in phase are aligned horizontally and the two haplotypes in each sire are separated using a solid line.
  4. 4 Haplotypes were numbered sequentially to allow comparison with haplotype effects (Table 6). Note that the loss of function mutation is present only within Hap4.