Figure 1From: The influence of gene-environment interactions on GHR and IGF-1 expression and their association with growth in brook charr, Salvelinus fontinalis (Mitchill)GH/IGF-1 axis. Illustration of the endocrine axis controlling growth in teleost fish. Multiple hormonal and nutritional factors may stimulate (+) the production and/or modify (+/-) the activity of IGF-1. Negative feedback (-) by IGF-1 inhibits growth hormone secretion by the pituitary.Back to article page