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Table 5 Correlation coefficients of hypertension-associated polymorphism MAFs with latitude.

From: Prevalence of common disease-associated variants in Asian Indians

Polymorphism Population Adjusted Spearman Rank Correlation Score Adjusted r2
CYP3A5 g.6980G>A CEPH-HGDP -0.621** 0.319
  CEPH-HGDP + HapMap -0.620** 0.349
  CEPH-HGDP + HapMap + AIP -0.603** 0.302
AGT g.802C>T CEPH-HGDP -0.718** 0.409
  CEPH-HGDP + Others -0.693** 0.373
  CEPH-HGDP + Others + AIP -0.518** 0.248
GNB3 g.825C>T Others -0.620** 0.278
  Others + AIP -0.300* 0.101
  1. * significant at 0.05, ** significant at 0.01
  2. CEPH-HGDP = Centre d'Etude du Polymorphisme Humain-Human Genome Diversity Panel.
  3. AIP = Asian Indian population.
  4. Others = data from other populations that were not part of CEPH-HGDP or HapMap.
  5. For sample sizes, please see Additional file 1, Tables S4, S5, S6, for CYP3A5 g.6980G>A, AGT g.802C>T, and GNB3 g.825C>T, respectively.