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Table 4 SNP haplotypes in DRD2 gene

From: Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes

aHaplotype DM (398) n*;f** CRI (380) n*;f** χ2 P O.R (95% CI)
111 217 (0.545) 173 (0.046) 4.97 0.03 0.69 (0.49–0.96)
211 56 (0.14) 40 (0.105) 1.65 0.20 0.73 (0.44–1.19)
112 18 (0.045) 39 (0.102) 6.94 0.01 2.37 (1.23–4.60)
212 14 (0.035) 00 (0.00) 6.23 0.01 0.09 (0.01–0.74)
121 11 (0.027) 38 (0.1) b 13.51 <<0.01 4.08 (1.83–9.11)
221 01 (0.002) 01 (0.002) 0.43 0.51 1.08 (0.08–17.32)
122 41 (0.103) 80 (0.21) b 12.94 <<0.01 2.33 (1.46–3.73)
222 39 (0.098) 09 (0.023) b 13.50 <<0.01 0.23 (0.10–0.54)
  1. aOrder of SNPs in the DRD2 haplotypes: -141 ins/del C – G>A (Intron 1) – T>C (Intron 7)
  2. bSignificant after Bonferroni's correction α = 0.0063
  3. *n = total number
  4. **f = frequency