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Table 2 Association analyses of CAPN1 polymorphisms with carcass traits (CW and MS) among Korean native cattle

From: A single nucleotide polymorphism in CAPN1 associated with marbling score in Korean cattle

     Genotype   
Trait Polymorphism Position Amino acid change C/C C/R R/R P P cor.
     N(LSMEAN ± SE) N(LSMEAN ± SE) N(LSMEAN ± SE)   
CW c.579G>A Exon5 K193K 187(309.56 ± 2.58) 177(311.93 ± 2.57) 53(314.91 ± 4.99) 0.33 NS
  c.630A>G Exon6 T210T 174(312.17 ± 2.61) 180(311.14 ± 2.53) 67(310.88 ± 4.20) 0.16 NS
  c.760-24T>C Intron6 . 210(312.93 ± 2.24) 161(306.26 ± 2.72) 43(319.27 ± 4.92) 0.11 NS
  c.843+330A>G Intron7 . 224(312.42 ± 2.21) 156(306.68 ± 2.65) 31(323.82 ± 6.18) 0.69 NS
  c.1199G>A Exon11 R400Q 417(311.43 ± 1.50) 3(294.47 ± 19.76) . 0.46 NS
  c.1588G>A Exon14 V530I 289(311.78 ± 1.93) 111(309.62 ± 3.27) 15(311.41 ± 9.12) 0.84 NS
  c.1611+104C>T Intron14 . 227(311.32 ± 2.26) 155(311.06 ± 2.74) 33(313.20 ± 5.98) 0.88 NS
  c.1869+235C>G Intron18 . 128(313.33 ± 3.15) 189(308.92 ± 2.50) 102(312.55 ± 3.23) 0.73 NS
  c.2151*479C>T 3'UTR . 342(311.37 ± 1.78) 65(304.72 ± 4.80) 5(321.32 ± 16.27) 0.49 NS
  c.2151*765A>G 3'UTR . 307(310.08 ± 2.01) 96(310.63 ± 4.15) 12(311.52 ± 11.10) 0.23 NS
  c.2151*832G>A 3'UTR . 335(311.67 ± 1.75) 75(309.30 ± 4.14) 4(315.85 ± 19.01) 0.84 NS
  c.2151*845A>G 3'UTR . 293(308.97 ± 2.07) 112(312.82 ± 3.75) 12(317.88 ± 10.33) 0.11 NS
  Block2_ht2 . . 300(310.77 ± 1.86) 95(314.78 ± 3.50) 15(300.73 ± 8.72) 0.85 NS
  Block2_ht3 . . 335(310.25 ± 1.80) 72(316.69 ± 4.68) 3(303.60 ± 20.41) 0.46 NS
MS c.579G>A Exon5 K193K 187(2.10 ± 0.10) 177(2.39 ± 0.10) 53(2.00 ± 0.19) 0.85 NS
  c.630A>G Exon6 T210T 174(2.19 ± 0.10) 180(2.29 ± 0.10) 67(2.09 ± 0.17) 0.64 NS
  c.760-24T>C Intron6 . 210(2.18 ± 0.09) 161(2.26 ± 0.11) 43(2.16 ± 0.20) 0.69 NS
  c.843+330A>G Intron7 . 224(2.18 ± 0.09) 156(2.21 ± 0.11) 31(2.16 ± 0.25) 0.78 NS
  c.1199G>A Exon11 R400Q 417(2.21 ± 0.06) 3(1.77 ± 0.79) . 0.47 NS
  c.1588G>A Exon14 V530I 289(2.21 ± 0.08) 111(2.24 ± 0.13) 15(2.12 ± 0.37) 0.60 NS
  c.1611+104C>T Intron14 . 227(2.19 ± 0.09) 155(2.17 ± 0.11) 33(2.56 ± 0.24) 0.22 NS
  c.1869+235C>G Intron18 . 128(2.30 ± 0.13) 189(2.23 ± 0.10) 102(2.12 ± 0.13) 0.09 NS
  c.2151*479C>T 3'UTR . 342(2.34 ± 0.07) 65(1.56 ± 0.19) 5(0.94 ± 0.65) 0.0007 0.02
  c.2151*765A>G 3'UTR . 307(2.19 ± 0.08) 96(2.33 ± 0.17) 12(2.67 ± 0.45) 0.08 NS
  c.2151*832G>A 3'UTR . 335(2.20 ± 0.07) 75(2.31 ± 0.17) 4(1.10 ± 0.76) 0.13 NS
  c.2151*845A>G 3'UTR . 293(2.15 ± 0.08) 112(2.42 ± 0.15) 12(2.77 ± 0.41) 0.06 NS
  Block2_ht2 . . 300(2.11 ± 0.07) 95(2.56 ± 0.14) 15(2.20 ± 0.35) 0.28 NS
  Block2_ht3 . . 335(2.14 ± 0.07) 72(2.54 ± 0.19) 3(2.28 ± 0.82) 0.21 NS
  1. Genotype and haplotype distributions and P-values controlling for sire and age at slaughter as covariates are shown.
  2. C/C, C/R, and R/R represent the common allele, and heterozygotes and homozygotes for the rare allele, respectively.
  3. N(LSMEAN ± SE): Number of animals (least square mean of values ± standard errors).
  4. Pcor.represents the simple corrected P-value (Bonferroni correction).
  5. Significant associations are shown in boldface. NS: not significant