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Table 3 Scg5 promoter polymorphisms in C57BL/6J, C57BL/6J-hg/hg, BALB/cByJ, C3H/HeJ, DBA/2J and CAST/EiJ strains

From: Overexpression of Scg5 increases enzymatic activity of PCSK2 and is inversely correlated with body weight in congenic mice

Strain Scg5 exp. -2475 (A/G) -2445 (A/C) -1540 (A/G) -1373 (A/G) -1095 (G/C) -904 (G/T) -794 (G/A) -659 (A/G) -432 (C/T) del-432 -306 (A/C)
C57BL/6J LOW AA AA AA GG GG GG GG AA CC + AA
C57BL/6J-hg/hg LOW AA AA AA GG GG GG GG AA CC + AA
BALB/cByJ HIGH AA AA AA AA GG GG AA GG del del N/A
C3H/HeJ HIGH AA AA AA AA GG GG AA GG del del N/A
DBA/2J HIGH AA AA AA AA GG GG AA GG del del N/A
CAST/EiJ HIGH GG CC GG AA CC TT AA GG TT + CC
  1. SNPs are numbered based on position upstream from transcription start site as defined by RefSeq NM_009162,. SNPs with genotypes in bold italics segregate low expressers and high expressers. +, deletion not present in these strains; del, deletion is present in these strains; N/A, genotypes for -306 were not determined for strains with deletion due to the forward primer sequence overlapping the deletion.