Combining identity by descent and association in genetic case-control studies

BMC Genomic Data

Table 2 Test results for observed data

Data	SNP	p _genotype	p _FP	p _allele	F _case	F _control
AMD	rs380390	0.0380	0.0090	0.0056	0.215	-0.073
	rs10272438	1.0000	0.9068	0.0194	0.733	0.611
AMD HK	rs10490924	0.0002	0.0002	0.0002	0.243	-0.062
	rs10504152	0.0058	0.1286	0.2222	0.132	-0.271
	rs584244	0.1824	0.0996	0.1010	-0.011	-0.149
PD	rs9952724	0.0004	0.0002	1.0000	0.788	0.022
	rs850084	0.0022	0.0002	0.9932	0.828	0.243
	rs10963676	0.0058	0.0004	0.0072	0.817	0.086
	rs4746675	0.0062	0.0004	1.0000	0.839	0.048
	rs557074	0.0068	0.0012	1.0000	0.736	0.029
	rs1504212	0.0088	0.0014	1.0000	0.494	-0.023
	rs12364577	0.0174	0.0020	1.0000	0.519	0.014
	rs1468375	0.0240	0.0042	0.0002	0.452	-0.040

Results of the genotype, FP, and allele tests applied to three published datasets: AMD in Caucasians [11], AMD HK in data from Hong Kong [15], and PD [16]. Estimated F values based on observed numbers of genotypes in case and control individuals are unrestricted, that is, may be negative.

ISSN: 2730-6844