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Table 7 Summary of average of two-gene genetic variance (mean) as the fraction of total phenotypic variance stratified into subpopulations by LCA.

From: Analysis of heterogeneity and epistasis in physiological mixed populations by combined structural equation modelling and latent class analysis

The significance level for inclusion of cases corrected for multiple comparisons is 6.1E-06
  Class Average genetic variance  
    Minimum Average Maximum Fraction
Women Total variance   29 97 270  
   LCA/non-LCAa 104 346 965  
     Additive variance   9 29 78 29.6%
   LCA/non-LCA 117 388 1,102  
     Dominant variance   6 19 50 19.3%
   LCA/non-LCA 104 332 864  
     Epistasis   14 50 153 51.1%
   LCA/non-LCA 105 378 1,143  
   Number of interactions   2,188     
   Fraction of possible   26.5%     
   Number of interactions/trait   156     
Men Total variance   39 97 430  
   LCA/non-LCA 118 299 1,357  
     Additive variance   9 29 118 30.0%
   LCA/non-LCA 97 296 1,226  
     Dominant variance   7 17 57 18.5%
   LCA/non-LCA 102 270 857  
     Epistasis   19 50 257 51.5%
   LCA/non-LCA 124 329 1727  
   Number of interactions   2,042     
   Fraction of possible   24,7%     
   Number of interactions/trait   146     
  1. aIncrease in average genetic variance in the classes relative to the genetic variance before stratification in to classes by LCA.