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Table 2 λS and sib-sib OR (with 95% CI) for PPROM.

From: Population-based estimate of sibling risk for preterm birth, preterm premature rupture of membranes, placental abruption and pre-eclampsia

 

All Races

White

Black

Population: PPROM

2105

1311

763

Population: N

254740

211308

39190

Population risk

0.008 (0.008–0.008)

0.006 (0.006–0.006)

0.019 (0.018–0.020)

Siblings: sibpairs with both siblings affected

88

37

49

Siblings: sibpairs with first sibling affected

1300

883

393

Sibling risk

0.068 (0.054–0.082)

0.042 (0.029–0.055)

0.125 (0.092–0.158)

λS

8.2 (6.5–9.9)

6.8 (4.6–8.9)

6.4 (4.7–8.1)

Sib-sib unadjusted OR (95% CI)

10.8 (8.6–13.5)

8.8 (6.3–12.4)

8.8 (6.4–12.1)

Sib-sib adjusted OR (95% CI)#

9.6 (7.6–12.2)

8.5 (6.0–12.1)

8.9 (6.4–12.5)

  1. #Adjusted for mother < 20 years old, mother < 12 education, Medicaid (index of low SES), no prenatal care, mother BMI < 20 kg/m2, cigarette smoking