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Table 4 λS and sib-sib OR (with 95% CI) for pre-eclampsia.

From: Population-based estimate of sibling risk for preterm birth, preterm premature rupture of membranes, placental abruption and pre-eclampsia

  All races White Black
Population: pre-eclampsia 8600 6749 1736
Population: N 267840 220505 42861
Population risk 0.032 (0.031–0.033) 0.031 (0.031–0.031) 0.041 (0.039–0.043)
Siblings: sibpairs with both siblings affected 1070 821 233
Siblings: sibpairs with first sibling affected 7384 5869 1400
Sibling risk 0.145 (0.137–0.153) 0.140 (0.131–0.149) 0.166 (0.146–0.186)
λS 4.5 (4.2–4.8) 4.5 (4.2–4.8) 4.1 (3.6–4.6)
Sib-sib unadjusted OR (95% CI) 9.2 (8.5–9.9) 10.0 (9.1–10.9) 6.7 (5.7–7.9)
Sib-sib adjusted OR (95% CI)# 8.1 (7.5–8.8) 9.0 (8.2–9.8) 5.8 (4.9–7.0)
  1. #Adjusted for mother < 20 or > 35 years old, mother < 12 education, Medicaid (index of low SES), no prenatal care, mother BMI < 20 kg/m2, cigarette smoking, insulin-dependent diabetes mellitus, chronic hypertension