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Figure 5 | BMC Genetics

Figure 5

From: A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples

Figure 5

Relation between the pattern of LD (x-axis) and the global measure of association (y-axis) in the regional filter. The pattern of LD is measured by the average of the Bayes D' between consecutive SNPs in the region, and the global measure of association is the joint probability of association in the region. The two figures in the top half show the relation using data from the study of fetal hemoglobin in the sickle cell anemia subjects. The two figure in the bottom half show the relation using data from the longevity study. The different extent of LD reflect the fact that sickle cell anemia subjects are all African American while centenarians in the longevity study are all Caucasians The correlations in the four sets are 0.03, 0.18, 0.018, -0.10.

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