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Figure 2 | BMC Genetics

Figure 2

From: Genetic dissection of susceptibility genes for diabetes and related phenotypes on mouse chromosome 14 by means of congenic strains

Figure 2

Diabetes-related phenotypes in NSY, C3H, C3H-Chr 14NSY(R0), C3H.NSY-( D14Mit206-D14Mit5 ) (R1) and C3H.NSY-( D14Mit206-D14Mit186 ) (R2) mice. A. Blood glucose levels during ipGTT in NSY (n = 16; ▲), C3H (n = 39; □) and R0 mice (n = 36; ■). B. Blood glucose levels during ipGTT in C3H (n = 39; □), R0 (n = 36; ■), R1 (n = 23; ) and R2 mice (n = 23; ). C. Fasting glucose level in NSY (n = 16), C3H (n = 39), R0 (n = 36), R1 (n = 23) and R2 mice (n = 23). D. Area under glucose concentration curve (gAUC) during ipGTT in NSY (n = 16), C3H (n = 39), R0 (n = 36), R1 (n = 23) and R2 mice (n = 23). E. Insulinogenic index in NSY (n = 20), C3H (n = 21), R0 (n = 15), R1 (n = 20) and R2 mice (n = 16). F. Insulin resistance assessed by decrease in glucose area in insulin tolerance test in NSY (n = 18), C3H (n = 18), R0 (n = 19), R1 (n = 23) and R2 mice (n = 22). *p < 0.05, **p < 0.01, ***p < 0.001 vs. C3H. p < 0.05, ††p < 0.01, †††p < 0.001 vs. R0.

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