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Table 1 Anatomical analysis of parental NSY and C3H mice, consomic R0 and congenic R1 and R2 mice at 30 weeks of age

From: Genetic dissection of susceptibility genes for diabetes and related phenotypes on mouse chromosome 14 by means of congenic strains

  Parental strains Consomic strain Congenic strains
  NSY C3H R0 R1 R2
Number of mice analyzed 9 20 15 12 15
Body weight (g) 43.5 ± 1.6c 29.5 ± 0.5 30.2 ± 0.6 30.8 ± 0.8 32.2 ± 0.6c,d
Anal-nasal length (cm) 11.0 ± 0.1c 10.2 ± 0.1 10.1 ± 0.1 10.1 ± 0.1 10.2 ± 0.1
BMI (g/cm2) 0.357 ± 0.007c 0.283 ± 0.005 0.294 ± 0.005 0.304 ± 0.005b 0.310 ± 0.005c,d
Total fat (g) 3.451 ± 0.260c 1.023 ± 0.052 1.385 ± 0.100b 1.390 ± 0.088c 1.683 ± 0.095c,d,f
Epididymal fat (g) 1.578 ± 0.106c 0.509 ± 0.033 0.723 ± 0.052b 0.730 ± 0.058b 0.880 ± 0.051c,e
Retroperitoneal fat (g) 1.083 ± 0.120c 0.119 ± 0.009 0.179 ± 0.018b 0.173 ± 0.013b 0.269 ± 0.019c,e,g
Mesenteric fat (g) 0.789 ± 0.059c 0.395 ± 0.020 0.483 ± 0.033a 0.487 ± 0.025b 0.534 ± 0.029c
Total fat / body weight (%) 7.85 ± 0.34c 3.49 ± 0.18 4.53 ± 0.26b 4.48 ± 0.22b 5.18 ± 0.21c,f
  1. Values are total number or mean ± SEM.
  2. NSY, C3H-Chr 14NSY (R0), C3H.NSY-(D14Mit206-D14Mit5) (R1), and C3H.NSY-(D14Mit206-D14Mit186) (R2) mice were compared with C3H (ap < 0.05, bp < 0.01, cp < 0.001). R1 and R2 mice were compared with R0 (dp < 0.05, ep < 0.01). R2 was compared with R1 (fp < 0.05, gp < 0.001).