Alteration in methylation level at 11β-hydroxysteroid dehydrogenase type 2 gene promoter in infants born to preeclamptic women

Table 2 Average methylation levels of HSD between male and female infants

Gender of neonater	Normal pregnancy		P value	Preeclampsia		P value
Gender of neonater	Male	Female	P value	Male	Female
TOTAL N	40	38		22	21
HSD9_CpG_1	0.13 ± 0.032	0.13 ± 0.023	0.943	0.12 ± 0.025	0.12 ± 0.037	0.989
HSD9_CpG_2	0.10 ± 0.022	0.11 ± 0.016	0.358	0.09 ± 0.020	0.10 ± 0.016	0.248
HSD9_CpG_3	0.40 ± 0.047	0.42 ± 0.048	0.087	0.38 ± 0.063	0.40 ± 0.047	0.481
HSD9	0.21 ± 0.030	0.22 ± 0.020	0.341	0.20 ± 0.030	0.21 ± 0.030	0.324
HSD23_CpG_1	0.16 ± 0.035	0.15 ± 0.036	0.103	0.16 ± 0.034	0.15 ± 0.038	0.417
HSD23_CpG_2	0.16 ± 0.092	0.17 ± 0.101	0.953	0.14 ± 0.032	0.13 ± 0.032	0.498
HSD23_CpG_3	0.15 ± 0.060	0.15 ± 0.070	0.839	0.12 ± 0.056	0.10 ± 0.038	0.235
HSD23	0.16 ± 0.045	0.16 ± 0.057	0.749	0.14 ± 0.030	0.13 ± 0.030	0.190

ISSN: 2730-6844