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Table 2 Association between the TCF7L2 rs7903146 SNP and the T2D risk in the ISOR study

From: The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population

 

ISOR

Non-T2D subjects

T2D subjects

 

Additive model (T vs C allele)

 

Dominant model (CT + TT vs CC)

 

Recessive model (TT vs CC + CT)

 
 

n (frequency)

n (frequency)

n (frequency)

p

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

n

720

644

76

       

CC

244 (0.39)

228 (0.35)

16 (0.21)

       

CT

328 (0.45)

287 (0.45)

41 (0.54)

0.04

1.55 (1.09-2.20)*

0.01*

2.26 (1.24-4.13)*

0.008*

1.46 (0.80-2.64)*

0.22*

TT

148 (0.20)

129 (0.20)

19 (0.25)

 

1.62 (1.13-2.31)

0.008

2.38 (1.30-4.36)

0.005

1.54 (0.85-2.82)

0.16

C allele

818 (0.57)

743 (0.58)

73 (0.48)

0.02

      

T allele

624 (0.43)

545 (0.42)

79 (52)

      
  1. The odds ratios (OR) (95% confidence interval (CI)) and the p values were obtained from logistic regression analyses using additive, dominant or recessive models, adjusted for *age, gender, physical activity and smoking status or age, gender, physical activity, smoking status and BMI.