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Table 2 Association between the TCF7L2 rs7903146 SNP and the T2D risk in the ISOR study

From: The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population

  ISOR Non-T2D subjects T2D subjects   Additive model (T vs C allele)   Dominant model (CT + TT vs CC)   Recessive model (TT vs CC + CT)  
  n (frequency) n (frequency) n (frequency) p OR (95% CI) p OR (95% CI) p OR (95% CI) p
n 720 644 76        
CC 244 (0.39) 228 (0.35) 16 (0.21)        
CT 328 (0.45) 287 (0.45) 41 (0.54) 0.04 1.55 (1.09-2.20)* 0.01* 2.26 (1.24-4.13)* 0.008* 1.46 (0.80-2.64)* 0.22*
TT 148 (0.20) 129 (0.20) 19 (0.25)   1.62 (1.13-2.31) 0.008 2.38 (1.30-4.36) 0.005 1.54 (0.85-2.82) 0.16
C allele 818 (0.57) 743 (0.58) 73 (0.48) 0.02       
T allele 624 (0.43) 545 (0.42) 79 (52)       
  1. The odds ratios (OR) (95% confidence interval (CI)) and the p values were obtained from logistic regression analyses using additive, dominant or recessive models, adjusted for *age, gender, physical activity and smoking status or age, gender, physical activity, smoking status and BMI.