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Table 3 Association between the TCF7L2 rs7903146 SNP and anthropometric, biochemical and clinical parameters in non-T2D subjects in the ISOR study

From: The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population

Parameter CC CT TT p
  (n = 228) (n = 287) (n = 129)  
Weight (kg) 72.1 ± 14.0 70.7 ± 15.2 67.7 ± 14.1 0.02
BMI (kg/m2) 26.4 ± 5.0 25.7 ± 5.1 24.9 ± 5.1 0.009
Waist (cm) 88.1 ± 12.2 86.1 ± 12.2 84.3 ± 11.9 0.01
Hip (cm) 102.5 ± 9.7 101.6 ± 9.6 100.6 ± 9.9 0.06
Waist-to-hip ratio 0.86 ± 0.09 0.85 ± 0.08 0.84 ± 0.08 0.02
Fasting glucose (mmol/L) 4.80 ± 0.50 4.75 ± 0.50 4.82 ± 0.49 0.34
Fasting insulin (μIU/mL) 8.58 ± 6.67 7.91 ± 5.40 6.88 ± 4.00 0.25
HOMA-IR 1.8 ± 1.4 1.7 ± 1.2 1.5 ± 0.9 0.36
HOMA-B 160.9 ± 172.5 144.7 ± 112.1 114.4 ± 72.9 0.08
Triglycerides (mmol/L) 1.14 ± 0.49 1.14 ± 0.45 1.02 ± 0.47 0.24
Total cholesterol (mmol/L) 4.43 ± 0.93 4.46 ± 0.89 4.38 ± 0.89 0.95
HDL-cholesterol (mmol/L) 1.25 ± 0.32 1.24 ± 0.29 1.30 ± 0.34 0.53
LDL-cholesterol (mmol/L) 2.67 ± 0.86 2.71 ± 0.85 2.64 ± 0.84 0.84
SBP (mmHg) 122.0 ± 16.2 122.5 ± 18.1 121.5 ± 16.9 0.23
DBP (mmHg) 75.9 ± 9.1 76.5 ± 10.8 76.2 ± 9.5 0.08
  1. Data are presented as the mean ± standard deviation.
  2. p values were adjusted for age, gender, smoking status and physical activity (plus BMI for biochemical and clinical variables). Statistically significant p values are indicated in bold type.