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Table 5 Impact of the rs7903146 SNP on anthropometric and glucose-related variables in non-T2D subjects, as a function of dessert intake

From: The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population

   Non-/low consumers Consumers/high consumers
Parameter Interaction p CC CT TT p CC CT TT p
N   79 87 41   147 199 88  
Weight (kg) 0.41 72.5 ± 14.0 69.6 ± 15.5 66.5 ± 12.5 0.04 71.8 ± 14.0 71.2 ± 15.0 68.3 ± 14.8 0.18
BMI (kg/m2) 0.83 26.5 ± 4.9 26.0 ± 5.3 24.7 ± 4.5 0.08 26.3 ± 5.1 25.6 ± 5.0 25.0 ± 5.3 0.06
Waist (cm) 0.60 89.3 ± 12.6 86.0 ± 12.0 84.5 ± 11.8 0.06 87.5 ± 11.9 86.1 ± 12.3 84.2 ± 12.0 0.10
Hip (cm) 0.87 102.0 ± 10.2 101.5 ± 9.0 99.9 ± 7.9 0.22 102.8 ± 9.4 101.6 ± 9.9 101.0 ± 10.8 0.13
Waist-to-hip ratio 0.24 0.88 ± 0.09 0.85 ± 0.08 0.84 ± 0.08 0.07 0.85 ± 0.08 0.85 ± 0.08 0.83 ± 0.08 0.28
Fasting glucose (mmol/L) 0.02 4.84 ± 0.49 4.81 ± 0.54 4.66 ± 0.53 0.29 4.78 ± 0.51 4.72 ± 0.48 4.89 ± 0.46 0.03
Fasting insulin (μIU/mL) 0.24 9.27 ± 7.69 8.83 ± 6.94 6.40 ± 3.83 0.20 8.21 ± 6.05 7.51 ± 4.54 7.10 ± 4.08 0.99
HOMA-IR 0.12 2.0 ± 1.5 1.9 ± 1.7 1.4 ± 0.9 0.16 1.8 ± 1.3 1.6 ± 1.0 1.6 ± 1.0 0.67
HOMA-B 0.41 167.5 ± 189.6 150.9 ± 125.5 120.7 ± 72.9 0.77 157.3 ± 163.1 141.9 ± 106.0 111.6 ± 72.8 0.08
  1. p values were adjusted for age, gender, smoking status and physical activity (plus BMI for glucose and insulin-related variables). Statistically significant p values are indicated in bold type.