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Figure 2 | BMC Genetics

Figure 2

From: Chromosome 16q22 variants in a region associated with cardiovascular phenotypes correlate with ZFHX3expression in a transcript-specific manner

Figure 2

Associations between SNP genotype and gene expression. SNPs are plotted with chromosomal position on the x axis and –log p value on the y axis. The horizontal line represents the significance threshold (p = 0.05). Individual points are coloured to indicate effect size (β). No SNP is significantly associated with whole gene expression. A single SNP, rs8060701, is significantly associated with allelic expression of both transcripts together. 11 SNPs are associated with allelic expression of the A transcript. The cartoon at top shows the position of transcripts A and B of ZFHX3. Both isoforms are transcribed in the reverse direction, arrow.

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