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Table 3 Associations of birth weight and newborn FTO genotypes or alleles

From: Does FTO have a paradoxical effect in fetal life?

  Exposure = Newborn FTO SNP
  Newborn weight (g) FTO rs9930506 SNP
  N Mean ± SD(g) P value vs 1°group* N Mean ± SD(g) P value vs 1°group*
Genotypes       
  Homozygous for non rish allele 167 3314 ± 378   165 3326 ± 386  
  Heterozygous 253 3238 ± 386 0,02 236 3236 ± 394 0,02
  Homozygous for risk allele 74 3157 ± 366 0,001 93 3161 ± 329 0,0006
   Mean difference (g) per newborn risk-allele for rs9939609 Mean difference (g) per newborn risk-allele for rs9930506
   Mean (95% CI) P value Mean (g) (95% CI) P value
Various adjustments     
  Unadjusted -78(-128; -28) 0,002 -83(-131; -36) 0,0006
  Adjusted for maternal allele -73(-130; -16) 0,09 -76(-132; -21) 0,007
  Adjusted for maternal allele and other variables** -56(-107; -5) 0,03 -55(-105; -6) 0,03
  Adjusted also for maternal BMI -50(-99; 0) 0,05 -48(-100; 0) 0,05
  Adjusted also for Adjusted also for weight gain -48(-98: +2) 0,06 -47(-95;+1) 0,06
  1. *Students T test.
  2. **Adjusted for sex, gestational age, panty and current smoking during pregnancy.