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Table 1 Results of the first screening

From: Identification of kinases and regulatory proteins required for cell migration using a transfected cell-microarray system

Gene a

Alias

Control

P value b

Vapa

 

Pxn

6.69E-13

Prkd1

Prkcm

Pxn

6.89E-09

Kit

 

Pxn

1.85E-07

Btk

 

Pxn

2.98E-07

Srp72_siteA

 

Pxn

1.61E-06

Tfg

 

Pxn

5.50E-06

Akap12

AKAP12A

Pxn

6.27E-06

Pard3

 

Pxn

1.02E-05

Cpne3

 

Pxn

1.12E-05

Pank2

 

Pxn

2.04E-05

Mapk8ip

JIP1

Pxn

6.26E-05

Map4k4

 

Pxn

2.00E-04

Mapk8ip3

JSAP1

Pxn

3.82E-04

Irak1bp1

 

Pxn

5.03E-04

Riok3

 

Pxn

7.00E-04

Trib3

NIPK

Pxn

1.40E-03

Prkca

Pkca

Pxn

2.60E-03

Srpk1

 

Pxn

2.90E-03

Cdk13

Cdc2l5

Pxn

4.00E-03

Bmpr1a

 

Pxn

4.00E-03

Rapgef3

Epac

Pxn

6.20E-03

Srp72_siteB

 

Pxn

6.40E-03

Mark1

 

Pxn

7.00E-03

Stk24

 

Pxn

7.17E-03

Brdt

 

Pxn

8.10E-03

Lyn

 

Pxn

8.70E-03

Camk2b

Ck2b

Pxn

8.90E-03

Zap70

Srk

Pxn

1.10E-02

Camkv

1G5

Pxn

1.20E-02

Tgfbr1

 

Pxn

1.80E-02

Ksr1

Ksr

Pxn

2.10E-02

Tyrobp

Karap

Pxn

2.40E-02

Ibtk

 

Pxn

2.70E-02

Ripk1

 

Pxn

3.20E-02

Pik3c2a

 

Pxn

4.10E-02

Cerk

 

Pxn

4.40E-02

Chka

Chk

Pxn

5.70E-02

Pik3ca

 

Pxn

8.90E-02

Flt3

 

Pxn

9.00E-02

Mob3c

Mobkl2c

Pxn

9.80E-02

Dstyk

Ripk5

NT

4.27E-06

Map2k6

Mkk6

NT

7.48E-06

Dapk1

 

NT

9.12E-06

Prps2

 

NT

1.85E-04

Vrk3

 

NT

6.84E-04

Clk4

 

NT

9.00E-04

Ugp2

 

NT

2.20E-02

Cdc42bpb

 

NT

5.05E-02

Dgkg

Dagk3

NT

6.50E-02

Ckmt1b

Ckmt1

NT

8.69E-02

Nek4

 

NT

9.97E-02

Zfp512b c

Urkl1

NT

1.20E-02

Ilk c

 

NT

8.30E-02

  1. aThe mean speeds of individual cells that expressed a test or control siRNA [non-target (NT) siRNA or anti-paxillin (Pxn) siRNA] were compared using the Mann-Whitney U-test (P < 0.1, control versus each siRNA). Fifty-one siRNAs, corresponding to 50 genes, had inhibitory effects on cell migration. bThe associated P-values are also shown. c The siRNAs that facilitated migration.