Gene | SNP | Patient | Control | Crude OR (95%CI) | Unadjusted p-value | Adjusted OR (95%CI) | Adjusted p-value | FDR corrected p-value |
---|---|---|---|---|---|---|---|---|
GNPTAB | rs17031962 | Â | Â | Â | Â | Â | Â | Â |
C Allele | 677 | 678 | 1.000 | Â | 1.000 | Â | Â | |
T Allele | 287 | 340 | 0.844 | 0.082 | 0.748 | 0.006 | 0.065 | |
(0.6977-1.022) | (0.6079-0.9209) | |||||||
CC | 240 | 222 | 1.000 | Â | 1.000 | Â | Â | |
CT | 197 | 234 | 0.779 | 0.062 | 0.674 | 0.007 | 0.074 | |
(0.5986-1.0131) | (0.5057-0.8977) | |||||||
TT | 45 | 53 | 0.785 | 0.279 | 0.672 | 0.093 | 0.326 | |
(0.5072-1.2161) | (0.4226-1.0687) | |||||||
Dom | Â | Â | 0.780 | 0.052 | 0.665 | 0.003 | 0.036 | |
(0.6074-1.002) | (0.5056-0.8739) | |||||||
Rec | Â | Â | 0.886 | 0.571 | 0.771 | 0.255 | 0.596 | |
(0.5831-1.346) | (0.4917-1.207) | |||||||
rs10778148 | Â | Â | Â | Â | Â | Â | Â | |
C Allele | 854 | 909 | 1.000 | Â | 1.000 | Â | Â | |
T Allele | 110 | 107 | 1.090 | 0.540 | 1.148 | 0.368 | 0.639 | |
(0.827-1.437) | (0.8501-1.55) | |||||||
CC | 386 | 403 | 1.000 | Â | 1.000 | Â | Â | |
CT | 82 | 103 | 0.831 | 0.260 | 0.899 | 0.547 | 0.976 | |
(0.6024-1.1468) | (0.6350-1.2722) | |||||||
TT | 14 | 2 | 7.308 | 0.009 | 7.250 | 0.014 | 0.286 | |
(1.6501-32.3685) | (1.5021-34.9920) | |||||||
Dom | Â | Â | 0.955 | 0.769 | 1.022 | 0.897 | 0.966 | |
(0.7001-1.301) | (0.731-1.43) | |||||||
Rec | Â | Â | 7.568 | 0.008 | 7.462 | 0.012 | 0.254 | |
(1.711-33.48) | (1.554-35.83) | |||||||
GNPTG | rs2887538 | Â | Â | Â | Â | Â | Â | Â |
G Allele | 713 | 709 | 1.000 | Â | 1.000 | Â | Â | |
A Allele | 253 | 309 | 0.814 | 0.040 | 0.850 | 0.132 | 0.401 | |
(0.6689-0.9909) | (0.6879-1.05) | |||||||
GG | 265 | 245 | 1.000 | Â | 1.000 | Â | Â | |
AG | 183 | 219 | 0.773 | 0.054 | 0.829 | 0.195 | 0.775 | |
(0.5944-1.0041) | (0.6243-1.1006) | |||||||
AA | 35 | 45 | 0.719 | 0.173 | 0.754 | 0.275 | 0.481 | |
(0.4473-1.1559) | (0.4533-1.2525) | |||||||
Dom | Â | Â | 0.763 | 0.034 | 0.815 | 0.138 | 0.454 | |
(0.5947-0.98) | (0.6225-1.068) | |||||||
Rec | Â | Â | 0.806 | 0.357 | 0.816 | 0.421 | 0.695 | |
(0.5083-1.277) | (0.4968-1.34) | |||||||
NAGPA | rs882294 | Â | Â | Â | Â | Â | Â | Â |
T Allele | 785 | 877 | 1.000 | Â | 1.000 | Â | Â | |
C Allele | 179 | 143 | 1.404 | 0.006 | 1.531 | 0.002 | 0.034 | |
(1.102-1.789) | (1.176-1.994) | |||||||
TT | 318 | 377 | 1.000 | Â | 1.000 | Â | Â | |
CT | 149 | 123 | 1.436 | 0.012 | 1.577 | 0.004 | 0.074 | |
(1.0837-1.9032) | (1.1609-2.1408) | |||||||
CC | 15 | 10 | 1.778 | 0.166 | 2.060 | 0.112 | 0.337 | |
(0.7880-4.0131) | (0.8443-5.0280) | |||||||
Dom | Â | Â | 1.462 | 0.006 | 1.611 | 0.002 | 0.036 | |
(1.113-1.921) | (1.197-2.169) | |||||||
Rec | Â | Â | 1.606 | 0.252 | 1.793 | 0.195 | 0.560 | |
(0.7144-3.61) | (0.742-4.333) |