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Figure 2 | BMC Genetics

Figure 2

From: Regulatory networks in retinal ischemia-reperfusion injury

Figure 2

Unique and common loop-motifs and individual molecular loop-components related to early (24 h) and late (7d) stages post-IR injury. At 0 h, there were no significant closed loop-motives. A. Closed loop-motifs. B. Transcripts (mRNAs) representing target genes. C. microRNAs (miRs). D. transcription factors (TFs). There were a higher number of loop motifs at 24 h than at 7d. Moreover, there were more representations of mRNAs, miRs and TFs at 24 h compared with the 7d, whether they were unique or common. The pattern of node relationships for the molecular components is typical in that the numbers of TF < miRs < mRNAs.

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