Figure 6

Sub-networks at 7d associated with 5 particular cellular processes all being a part of the larger regulatory network seen in Figure 3B. A. Loop-motifs related to cell death. B. Loop-motifs related to antigen presentation. C. Loop-motifs associated with ion transport. D. Loop-motifs associated with immune responses. E. Loop-motifs associated with inflammatory responses. The thicker edges highlight the loop motifs that involve rno-miR-185. This miR has been associated with inflammatory responses during brain ischemic stroke in mice and is potential target for prevention and treatment of stroke (ref. [65]). Green filled circles denote miRs, red filled circles denote TFs and blue filled circles denote target genes/transcripts.