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Table 5 Standard error of estimated QTN location by simulation, as a function of G 3 population size (N) 1

From: Targeted Recombinant Progeny: a design for ultra-high resolution mapping of Quantitative Trait Loci in crosses between inbred or pure lines

N

k = 2

5

10

23

30

40

50

sSIM

sDET

L = 0.57

1000

2.0700

0.7220

0.3340

0.2030

0.1890

0.1820

0.1820

1.37

0.65

3000

0.7640

0.1180

0.0974

0.0959

0.0936

0.0921

0.0926

2.70

1.95

5000

0.4200

0.0993

0.0758

0.0734

0.0711

0.0728

0.0712

3.51

3.25

7000

0.1270

0.0905

0.0659

0.0580

0.0569

0.0581

0.0575

4.35

4.56

9000

0.1140

0.0895

0.0587

0.0500

0.0493

0.0491

0.0485

5.15

5.86

11000

0.1200

0.0859

0.0575

0.0499

0.0494

0.0472

0.0453

5.52

7.16

L = 0.77

1000

1.8100

0.3700

0.1890

0.1730

0.1680

0.1710

0.1700

1.47

0.65

3000

0.4950

0.1090

0.0964

0.0909

0.0894

0.0900

0.0883

2.83

1.95

5000

0.1380

0.0943

0.0723

0.0691

0.0680

0.0681

0.0672

3.72

3.25

7000

0.1330

0.0864

0.0659

0.0570

0.0551

0.0553

0.0559

4.47

4.56

9000

0.1310

0.0828

0.0597

0.0499

0.0489

0.0492

0.0494

5.06

5.86

11000

0.1280

0.0844

0.0567

0.0490

0.0461

0.0458

0.0460

5.43

7.16

  1. 1Abbreviations and assumptions: Standard error of estimated QTN location (SEQTN) by simulation, as a function of G3 population size (N), family size, (I); location of the QTN within its confidence interval (L) and number of markers spanning the QTL (k). sSIM, reduction factor according to the simulation analysis; sDET, reduction factor according to the deterministic analysis. Standardized allele substitution effect at the QTN = 0.2; number of G2R families, F = 25