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Table 2 Hazard ratios for risk factors on risk of CRC: The Korean Cancer Prevention Study-II and the KCPS-II sub-cohort

From: A colorectal cancer prediction model using traditional and genetic risk scores in Koreans

   KCPS-II cohort (Whole participants) KCPS-II sub-cohort (Case-cohort design)
Traditional risk factors   HR (95% CI) HR (95% CI)
Age, year   1.07 (1.06-1.08) 1.08 (1.07-1.10)
Sex (female)   0.65 (0.45-0.92) 0.71 (0.50-1.11)
Log (fasting serum glucose), mg/dL   1.81 (0.99-3.30) 2.16 (0.96-4.83)
Smoking status Ex-smoker 1.45 (1.03-2.05) 1.74 (1.12-2.72)
  Current smoker 1.28 (0.90-1.83) 1.40 (0.91-2.17)
Exercise (yes)   0.91 (0.70-1.17) 0.68 (0.49-0.94)
Family history of CRC (yes)   2.40 (1.34-4.30) 3.49 (1.70-7.17)
Per 1 SD of TRS increase   1.34 (1.29-1.39) 1.30 (1.24-1.36)
  1. CRC: colorectal cancer, HR: hazard ratios, CI: confidence interval, SD: standard deviation, TRS: traditional risk score,
  2. TRS combined information on above 6 risk factors: age, sex, fasting serum glucose, exercise, and family history of CRC.
  3. KCPS-II: The Korean Cancer Prevention Study-II.