Table 2 Association between Loci Identified in Populations of European Ancestry and Serum Magnesium in African-American Populations

Locus

Index SNP in ARIC AA participants

Chr

Position

Coded/Non-coded allele

Coded allele freq.

Beta

SE

P-Value

Imput. qual.

Coded allele freq.

Beta

P-Value

Imput. qual.

Beta

P-Value

P-Value threshold in region

MUC1

rs2974937

1

155168849

C/T

0.32

−0.013

0.002

6.1E-09

0.95

0.35

−0.007

3.5E-02

0.99

−0.012

2.1E-11

8.9E-04

MDS1

rs74516251

3

168830777

A/G

0.11

−0.013

0.003

1.6E-04

0.99

0.11

−0.005

3.3E-01

0.97

−0.011

2.0E-05

4.9E-04

SHROOM3

rs9993810

4

77614640

A/G

0.47

−0.008

0.002

1.8E-04

0.92

0.48

−0.008

3.5E-02

0.93

−0.008

6.1E-06

7.4E-04

TRPM6

rs113607577

9

77455459

G/C

0.90

−0.019

0.004

1.1E-07

0.90

0.89

−0.012

4.7E-02

0.87

−0.017

4.6E-07

1.5E-03

DCDC51

rs7947033

11

30795987

C/T

0.10

−0.011

0.004

5.4E-03

0.74

0.08

−0.001

8.3E-01

0.91

−0.008

1.4E-02

1.0E-03

ATP2B11

rs36089488

12

90118300

T/C

0.95

−0.015

0.005

5.0E-03

0.78

0.94

−0.013

1.0E-01

0.85

−0.015

6.5E-04

9.8E-04

HOXD91

rs6745764

2

176974122

G/A

0.67

−0.008

0.002

9.5E-04

0.82

0.69

−0.005

1.9E-01

0.90

−0.007

3.1E-05

8.5E-04

LUZP2

rs11027876

11

24412973

G/C

0.18

−0.009

0.003

1.3E-03

0.86

0.18

−0.001

8.3E-01

0.89

−0.007

8.1E-03

6.4E-04

PRMT7

rs55857142

16

68236741

T/A

0.07

−0.018

0.004

2.7E-05

0.95

0.07

0.006

3.5E-01

0.97

−0.012

7.1E-04

9.4E-04