Table 4 Association between Index SNPs at TRPM6 and Serum Magnesium by Fasting Insulin Levels in ARIC European and African Americans
N | Beta (mmol/L) | SE | P-Value | Variance explained | P for interaction | |
|---|---|---|---|---|---|---|
European-Americans (rs11144134 T allele, frequency 0.92) | ||||||
Fasting insulin < 80pmol/L | 5937 | −0.013 | 0.002 | 1.6E-07 | 0.44 % | 0.03 |
Fasting insulin ≥ 80pmol/L | 2752 | −0.008 | 0.003 | 1.8E-02 | 0.19 % | |
African-Americans (rs113607577 G allele, frequency 0.90) | ||||||
Fasting insulin < 80pmol/L | 1186 | −0.026 | 0.006 | 3.5E-06 | 1.55 % | 0.24 |
Fasting insulin ≥ 80pmol/L | 1302 | −0.014 | 0.005 | 9.0E-03 | 0.58 % | |