BMC Genomic Data

Table 1 Analysis of initial body weight, age and gender on disease phenotypes

From: Host genetic diversity influences the severity of Pseudomonas aeruginosa pneumonia in the Collaborative Cross mice

A	Survival Time (n = 92)			Change in BW day 1 (n = 92)
Initial body weight	r = 0.192 P > 0.05			r = 0.010 P > 0.05
Week’s old	r = 0.099 P > 0.05			r = 0.173 P > 0.05
Gender	r = 0.070 P > 0.05			r = 0.035 P > 0.05
B
Mean Survival Time
	Male			Female			ANOVA
	Mean	SEM	n	Mean	SEM	n	P value
A/J	1.83	0.60	3	4.67	1.06	6	P > 0.05
IL 4052	1.83	0.33	3	1.50	0.00	3	P > 0.05
IL 3438	7.00	0.00	3	7.00	0.00	3	P > 0.05
IL 2156	7.00	0.00	3	3.67	1.69	3	P > 0.05
IL 711	1.50	0.00	2	1.30	0.12	5	P > 0.05
IL 2126	1.50	0.00	4	1.50	0.00	2	P > 0.05
IL 4141	4.25	2.75	2	4.50	1.46	4	P > 0.05
IL 4457	5.17	1.36	3	2.50	0.00	2	P > 0.05
IL 1912	1.17	0.17	3	2.00	0.50	3	P > 0.05
% Change in body weight day 1
	Male			Female			ANOVA
	Mean	SEM	n	Mean	SEM	n	P value
A/J	−10.53	5.90	2	−11.30	1.11	5	P > 0.05
IL 4052	−3.05	0.94	3	−6.37	0.91	3	P > 0.05
IL 3438	−6.52	0.79	3	−4.28	0.47	3	P > 0.05
IL 2156	−5.69	1.75	3	−5.18	1.41	3	P > 0.05
IL 711	−5.13	1.30	2	−5.10	1.23	2	P > 0.05
IL 2126	−6.18	1.19	4	−5.15	0.49	2	P > 0.05
IL 4141	−8.45	1.27	2	−6.62	0.43	4	P > 0.05
IL 4457	−3.76	1.41	3	−5.23	2.03	2	P > 0.05
IL 1912	−6.36	0.00	1	−6.29	0.59	3	P > 0.05

Overall Spearman‘s correlation (r correlation coefficients and P value) between all the initial parameters (initial BW, week’s old and gender) of CC lines and recorded traits (ST: n = 92, CBW1: n = 92) to determine potential influence (A). Two-way ANOVA’s comparison across eight selected CC lines and A/J commercial inbred line to evaluate gender influence on recorded traits (MST and CWB1) (B)

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