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Fig. 5 | BMC Genetics

Fig. 5

From: Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model

Fig. 5

New and traditional ethnic classification to assess TB susceptibility in MCP-1 -2518 GG genotype carriers. The homogenous co-dominant model (GG vs AA) shows that people who carry the GG genotype have 3.49 times the risk to develop pulmonary TB compared to people who have the AA genotype. The magnitude of the association in the Asian continent according to the traditional classification appears diluted because it includes South Asia and Persia, which have different ancestry and increase the heterogeneity in this continent. For Latin America, similarly to the traditional ethnic classification, we find that subjects with the GG genotype have 2.72 times the risk to develop pulmonary TB

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