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Table 3 Haploview marker associations showing frequencies of the recessive alleles

From: Serum bilirubin concentration is modified by UGT1A1 Haplotypes and influences risk of Type-2 diabetes in the Norfolk Island genetic isolate

SNP

Associated allele

High bili allele freq

Normal bili allele freq

OR (95 % CI)

Chi square

P value

rs2741012

T

0.415

0.188

0.33 (0.22 – 0.49)

31.93

1.60E-08

rs2741023

A

0.431

0.239

0.41 (0.28 – 0.61)

20.06

7.52E-06

rs2741027

A

0.415

0.188

0.33 (0.22 – 0.49)

31.93

1.60E-08

rs7586110

G

0.500

0.251

0.33 (0.23 – 0.49)

32.33

1.30E-08

rs10168155

T

0.654

0.326

0.26 (0.17 – 0.38)

48.96

2.62E-12

rs10168416

G

0.492

0.194

0.25 (0.17 – 0.37)

51.93

5.75E-13

rs4485562

G

0.800

0.626

0.42 (0.26 – 0.66)

14.44

1.00E-04

rs10171367

G

0.654

0.326

0.26 (0.17 – 0.38)

48.96

2.62E-12

rs10179094

A

0.500

0.249

0.33 (0.22 – 0.49)

32.83

1.01E-08

rs7608175

G

0.654

0.326

0.26 (0.17 – 0.38)

49.11

2.42E-12

rs1105880

C

0.646

0.271

0.20 (0.14 – 0.30)

68.04

1.60E-16

rs2070959

G

0.492

0.194

0.25 (0.17 – 0.37)

51.93

5.75E-13

rs1105879

G

0.646

0.271

0.20 (0.14 – 0.30)

68.04

1.60E-16

rs17863787

G

0.623

0.249

0.20 (0.13 – 0.30)

70.15

5.51E-17

rs6725478

T

0.631

0.300

0.25 (0.17 – 0.37)

51.58

6.88E-13

rs6744284

T

0.577

0.222

0.21 (0.14 – 0.31)

66.86

2.91E-16

rs4294999

G

0.715

0.429

0.30 (0.21 – 0.45)

35.46

2.61E-09

rs2008595

A

0.715

0.429

0.30 (0.21 – 0.45)

35.46

2.61E-09

rs4663963

G

0.715

0.429

0.30 (0.21 – 0.45)

35.46

2.61E-09

rs2221198

T

0.672

0.402

0.33 (0.22 – 0.49)

31.32

2.18E-08

rs4124874

C

0.715

0.427

0.30 (0.21 – 0.45)

35.86

2.12E-09

rs3755319

G

0.715

0.427

0.30 (0.21 – 0.45)

35.86

2.12E-09

rs887829

A

0.623

0.254

0.20 (0.14 – 0.30)

67.92

1.70E-16

rs6742078

T

0.623

0.253

0.20 (0.14 – 0.30)

68.23

1.46E-16

rs4148324

G

0.623

0.254

0.20 (0.14 – 0.30)

67.92

1.70E-16

rs3771341

T

0.577

0.227

0.22 (0.15 – 0.32)

64.55

9.40E-16

rs4148325

T

0.623

0.254

0.20 (0.14 – 0.30)

67.92

1.70E-16

rs4148326

C

0.715

0.427

0.30 (0.21 – 0.45)

35.86

2.12E-09

rs2361502

C

0.546

0.268

0.30 (0.21 – 0.45)

38.61

5.16E-10

  1. Note: odds ratios are not adjusted for age and sex
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BMC Genomic Data

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