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Fig. 8 | BMC Genetics

Fig. 8

From: Freeze–thaw Caenorhabditis elegans freeze–thaw stress response is regulated by the insulin/IGF-1 receptor daf-2

Fig. 8

daf-16 target genes acs-19 and srh-99 are required for daf-2(rf) enhanced freezing survival. acs-19 and srh-99 RNAi reduced daf-2(e1370) and wild-type animals’ freeze–thaw survival. Sup-37 or lig-1 RANi had no significant effects on daf-2(e1370) and wild-type worms’ freeze-thaw survival . Every assay was repeated at least five times (n > 150–187) in the same conditions. Statistical significance was assessed by the Mann–Whitney test. *p < 0.05, **p < 0.01

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