Table 3 Genes differentially expressed in ISIAH versus WAG renal cortex and annotated in databases as associated with hypertension and blood pressure regulation

Ace ^{a bc}

NM_012544.1

Angiotensin I converting enzyme

−1.18

Acsm3 ^c

XM_006230106.1

Acyl-CoA synthetase medium-chain family member 3, transcript variant X2

2.51

Adra1b ^b

NM_016991.2

Adrenoceptor alpha 1B

−1.24

Adra2a

NM_012739.3

Adrenoceptor alpha 2A

−1.01

Alas1

NM_024484.2

Aminolevulinate, delta-, synthase 1

0.47

Angpt1

XM_006241609.1

Angiopoietin 1, transcript variant X1

0.69

Apob ^{a bc}

NM_019287.2

Apolipoprotein B

−2.52

Arg2 ^{a c}

NM_019168.1

Arginase 2

−0.58

Cdo1

XM_006254698.1

Cysteine dioxygenase type 1, transcript variant X1

−0.78

Clu ^{a c}

XM_006252094.1

Clusterin, transcript variant X1

−1.75

Comt

NM_012531.2

Catechol-O-methyltransferase

−0.82

Cst3 ^{a bc}

NM_012837.1

Cystatin C

−0.50

Cyp1a1 ^c

NM_012540.2

Cytochrome P450, family 1, subfamily a, polypeptide 1

−1.04

Cyp2j4 ^a

NM_023025.2

Cytochrome P450, family 2, subfamily j, polypeptide 4

−0.81

Cyp4a8

NM_031605.2

Cytochrome P450, family 4, subfamily a, polypeptide 8

−0.55

Ephx1 ^c

NM_012844.3

Epoxide hydrolase 1, microsomal (xenobiotic), transcript variant 2

0.59

Ephx2 ^{a b}

XM_006252147.1

Epoxide hydrolase 2, cytoplasmic, transcript variant X1

4.48

Gja1 ^c

XM_006256503.1

Gap junction protein, alpha 1, transcript variant X2

0.54

Glp1r

XR_362044.1

Glucagon-like peptide 1 receptor, transcript variant X1

3.79

Hsd11b2 ^c

NM_017081.2

Hydroxysteroid 11-beta dehydrogenase 2

0.60

Itgav ^b

XM_006234437.1

Integrin, alpha V

−0.62

Klk1c12 ^ab

NM_001005382.1

Kallikrein 1-related peptidase C12

−1.86

Klkb1 ^ac

XM_006253121.1

Kallikrein B, plasma 1, transcript variant X1

2.22

Mif ^bc

NM_031051.1

Macrophage migration inhibitory factor (glycosylation-inhibiting factor)

0.50

Mmp9 ^ac

XM_006235619.1

Matrix metallopeptidase 9, transcript variant X1

−2.49

Mthfr ^ac

XM_006239414.1

Methylenetetrahydrofolate reductase (NAD(P)H), transcript variant X2

0.49

Ppara ^bc

XM_006242154.1

Peroxisome proliferator activated receptor alpha, transcript variant X4

−0.56

Ptgds ^{a b}

NM_013015.2

Prostaglandin D2 synthase (brain)

−0.67

Ptk2b ^bc

XM_006252145.1

Protein tyrosine kinase 2 beta, transcript variant X3

−0.51

Ren ^a

NM_012642.4

Renin

−0.49

RT1-Bb ^c

NM_001004084.2

RT1 class II, locus Bb

−0.78

Slc26a4

XM_006239978.1

Solute carrier family 26 (anion exchanger), member 4, transcript variant X3

0.46

Slc2a4 ^b

NM_012751.1

Solute carrier family 2 (facilitated glucose transporter), member 4

−0.77

Slc9a3r2

XM_006245893.1

Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2, transcript variant X2

−0.48

Sncg

NM_031688.1

Synuclein, gamma (breast cancer-specific protein 1)

−1.25

Sts

XM_006256960.1

Steroid sulfatase (microsomal), isozyme S, transcript variant X1

−0.70

Tf ^{a bc}

NM_001013110.1

Transferrin

−1.50

Vwf ^bc

NM_053889.1

Von Willebrand factor

0.77

Xdh ^{a c}

NM_017154.1

Santhine dehydrogenase

−0.77

Guca2b

NM_022284.2

Guanylate cyclase activator 2B

2.04

P2rx4

NM_031594.1

Purinergic receptor P2X, ligand-gated ion channel 4

−1.65

Pcsk5

XM_006231145.1

Proprotein convertase subtilisin/kexin type 5, transcript variant X2

0.53