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Fig. 2 | BMC Genetics

Fig. 2

From: Above and beyond state-of-the-art approaches to investigate sequence data: summary of methods and results from the population-based association group at the Genetic Analysis Workshop 19

Fig. 2

Illustration of the evolutionary history of a particular genetic variant represented by a phylogeny tree. In the phylogenetic tree, time moves from past (left) to present (right). Suppose some of the variants represented in this tree are associated with a trait. Then, a large covariance is expected among trait values from 2 variants (eg, the blue diamonds) sharing a large portion of their evolutionary history (shown by the branches in blue). In contrast, the 2 variants denoted by black circles share a smaller portion of evolutionary history, so that little covariance in the corresponding trait values is expected

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