Sex-specific genetic determinants for arterial stiffness in Dahl salt-sensitive hypertensive rats

BMC Genomic Data

Table 4 QTLs for blood pressure and arterial stiffness in F2 (Dahl S x R) intercross rats

QTL	Trait	F2 cohort	Chr: location	Reference
AS-1	STR_aorta	M + F	Chr3: 40–60 Mbp
AS-m1	PWV_aorta	M	Chr4: 163–183 Mbp
AS-m2	PWV_aorta	M	Chr16: 6–26 Mbp
BP-m1	SBP	M	Chr1: 142–162 Mbp	[7]
BP-m2	SBP	M	Chr1: 189–209 Mbp	[7]
BP-m3	SBP	M	Chr20: 42–62 Mbp	[7]
BP-m4	SBP	M	Chr2: 194–214 Mbp	[7]
BP-m5	SBP	M	Chr11: 34–54 Mbp	[7]
AS-f1	PWV_aorta	F	Chr9: 15–35 Mbp
AS-f2	PWV_aorta	F	Chr11: 13–33 Mbp
BP-f1	SBP	F	Chr5: 135–155 Mbp	[7]
BP-f2	SBP	F	Chr5: 103–123 Mbp	[7]
BP-f3	SBP	F	Chr12: 4–24 Mbp	[7]
BP-f4	SBP	F	Chr2: 179–199 Mbp	[7]
BP-f5	SBP	F	Chr2: 96–116 Mbp	[7]
BP-f6	SBP	F	Chr1: 146–166 Mbp	[7]
ixBP-f1	SBP	F	Chr1: 189–209 Mbp	[7]
ixBP-f2	SBP	F	Chr3: 115–135 Mbp	[7]
ixBP-f3	SBP	F	Chr14: 63–83 Mbp	[7]
BP-pm1	SBP	pmF	Chr13: 73–93 Mbp	[8]
BP-pm2	SBP	pmF	Chr11: 53–73 Mbp	[8]
BP-pm3	DBP	pmF	Chr2: 254–270 Mbp	[8]
BP-pm4	DBP	pmF	Chr4: 164–184 Mbp	[8]
BP-pm5	SBP	pmF	Chr15: 18–38 Mbp	[8]

QTL quantitative trait locus, Chr chromosome, PWV _aorta Pulse Wave Velocity in aorta, STR _aorta strain in aorta, M F2 male cohort, F F2 female cohort, pmF F2 post-menopausal female cohort, BP blood pressure, AS arterial stiffness, Mbp mega base pairs

ISSN: 2730-6844