Table 5 Candidate genes for arterial stiffness QTLs detected with significant linkage in F2 (Dahl S x R) rat intercross
From: Sex-specific genetic determinants for arterial stiffness in Dahl salt-sensitive hypertensive rats
QTL | QTL-location | Trait | Symbol | Location | Description |
|---|---|---|---|---|---|
AS-1 | Chr3: 40–60 Mbp | Strain | ACVR1 | 44.6 Mbp | Activin A receptor, Type 1 |
AS-m1 | Chr4: 163–183 Mbp | PWV |  |  |  |
AS-m2 | Chr16: 6–26 Mbp | PWV |  |  |  |
AS-f1 | Chr9: 15–35 Mbp | PWV | VEGF A | 17.4 Mbp | Vascular endothelial growth factor A |
AS-f2 | Chr11: 13–33 Mbp | PWV | ADAMTS 1 | 25.4 Mbp | A Disintegrin And Metalloproteinase (ADAM) with thrombospondin type 1 motif, 1 |