Table 2 Pathways enriched in lung focally exposed to high-dose radiation of 90 Gy

mmu05414

Dilated cardiomyopathy

3.31E-09

6.08E-07

mmu04060

Cytokine-cytokine receptor interaction

5.25E-17

6.78E-15

mmu04115

p53 signaling pathway

4.94E-09

1.78E-07

mmu05410

Hypertrophic cardiomyopathy

1.75E-07

1.61E-05

mmu05322

Systemic lupus erythematosus

2.32E-10

1.50E-08

mmu05412

Arrhythmogenic right ventricular cardiomyopathy

5.71E-06

3.50E-04

mmu05332

Graft-versus-host disease

1.34E-09

5.78E-08

mmu04020

Calcium signaling pathway

1.24E-05

5.71E-04

mmu05330

Allograft rejection

1.81E-09

5.83E-08

mmu00982

Drug metabolism

1.85E-05

6.81E-04

mmu04142

Lysosome

2.10E-09

5.42E-08

mmu04530

Tight junction

1.15E-04

3.53E-03

mmu04612

Antigen processing and presentation

4.62E-09

9.93E-08

mmu04360

Axon guidance

1.58E-04

4.14E-03

mmu04940

Type I diabetes mellitus

7.14E-09

1.32E-07

mmu05310

Asthma

2.00E-08

3.23E-07

mmu04062

Chemokine signaling pathway

7.04E-08

1.01E-06

mmu04514

Cell adhesion molecules (CAMs)

1.51E-07

1.94E-06

mmu04650

Natural killer cell mediated cytotoxicity

2.78E-07

3.26E-06

mmu04672

Intestinal immune network for IgA production

9.21E-07

9.90E-06

mmu05340

Primary immunodeficiency

1.10E-05

1.09E-04

mmu05320

Autoimmune thyroid disease

1.11E-05

1.03E-04

mmu05416

Viral myocarditis

1.25E-05

1.08E-04

mmu04660

T cell receptor signaling pathway

1.95E-05

1.57E-04

mmu04640

Hematopoietic cell lineage

1.55E-04

1.17E-03

mmu04666

Fc gamma R-mediated phagocytosis

5.51E-04

3.94E-03

mmu04610

Complement and coagulation cascades

8.61E-04

5.82E-03

mmu04621

NOD-like receptor signaling pathway

9.22E-04

5.93E-03

mmu04670

Leukocyte transendothelial migration

1.19E-03

7.32E-03

mmu04662

B cell receptor signaling pathway

1.43E-03

8.41E-03

KEGG ID

Name

p-value

FDR

ID

Name

p-value

FDR

ID

Name

p-value

FDR

mmu00982

Drug metabolism

8.90E-06

1.67E-03

mmu04060

Cytokine-cytokine receptor interaction

3.39E-08

2.89E-06

NA

NA

NA

NA

mmu05410

Hypertrophic cardiomyopathy

8.99E-05

8.41E-03

mmu04062

Chemokine signaling pathway

1.36E-05

5.80E-04

mmu04260

Cardiac muscle contraction

1.36E-04

8.46E-03

mmu04620

Toll-like receptor signaling pathway

2.68E-05

7.58E-04

mmu04010

MAPK signaling pathway

1.80E-04

8.44E-03

mmu05414

Dilated cardiomyopathy

1.93E-04

7.24E-03