Network median joining. Haplotype network based on the sequences of variants (rs7903146, rs7896811, rs11196199, rs114863326, rs11196203, rs72826075 and rs35011184) of the samples of the 1000 Genomes Project associated with T2D. The nodes are the haplotype profiles and mv-nodes are the missing haplotypes. The outgroup included nucleotides from chimpanzee, root, macaque and orangutan. Each color indicates a possible haplotype profile; the color was randomly assigned. The size of the sphere is related to the frequency of the haplotype patterns. The dotted blue line includes the haplotypes from the African population, and the dotted green line contains the haplotype patterns of the European population. The bottom left of the figure shows the populations included in the network. The bottom right lists the mutations associated with T2D from the Sigma Project.