Fig. 4

Chromosome 2 genotypes and phenotypic summary of the congenic strains. The white and black bars indicate the genomic region from ICGN and B6 mice, respectively. The shaded bar shows an unclear genomic region in which recombination occurred. If a phenotypic severity was significantly alleviated by genetic recombination compared to that of ICGN mice (see Fig. 5 and Additional file 1: Figure S2), it is defined as resistant (R). If not, it is defined as susceptible (S). Tns2 ^nph-induced tubulointerstitial fibrosis related locus, Ttir, is located in rs33151033-D2Mit378 (49.5–68.8 Mb). Tns2 ^nph-induced podocyte injury related locus, Tpir, is located in D2Mit102-D2Mit409 (114.1–158.5 Mb)