Fig. 1

Transcription regulatory element atlas for Tst gene. Schematic presentation of predicted and experimentally validated data about mouse Tst transcription regulation, obtained from various genomics resources. Tst gene structure: white boxes – 3′ and 5′ UTR; black boxes – exons; white line – intron region. a Grey boxes show constrained elements betwen 39 Eutherian mammals. b DNAseI sites are presented as grey boxes and peaks (inverted triangles). c Black lines present predictions of TF binding sites. Grey stripes present ENCODE data with peaks (inverted triangles) for TFBS (c) histone modifications (d) and RNA polymerase binding sites (e). f The degree of DNA methylation is presented as a height line (100% methylation - the heighest line, 0% methylation - the lowest line). g Grey stripes present predicted CpG islands from various prediction tools. h Black lines display predicted miRNA target sites