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Table 1 Body weight, body mass index, food intake, and body composition of A/J and A/J-12SM strains fed the high-fat diet for 7 weeks

From: Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12

 

A/J (n = 9)

A/J-12SM (n = 10)

P-value

Initial body weight (g)a

21.6 ± 0.4

21.3 ± 0.4

NS

Final body weight (g)b

36.2 ± 1.0

34.4 ± 0.7

NS

Body mass index (g/cm2)

0.311 ± 0.006

0.301 ± 0.006

NS

Food intake (g/week)

20.3 ± 0.3

20.0 ± 0.3

NS

Weights of tissue (g/100 g bw)

   

Liver

4.00 ± 0.06

3.55 ± 0.08**

0.0003

Subcutaneous fatc

3.30 ± 0.19

3.21 ± 0.15

NS

Epididymal fat

5.21 ± 0.14

5.56 ± 0.24

NS

Retroperitoneal fat

1.45 ± 0.09

1.39 ± 0.09

NS

Mesenteric fat

2.75 ± 0.14

2.47 ± 0.12

NS

Blood glucose (mg/dl)

224.5 ± 5.5

192.7 ± 7.8**

0.0047

Serum insulin (ng/ml)

1.81 ± 0.23

1.08 ± 0.12*

0.0109

  1. Each value is expressed as the mean ± SEM
  2. *P < 0.05, **P < 0.01, significant difference from the value of A/J by Student’s t-test
  3. aInitial body weight was measured at 6 weeks of age (at 0 weeks of feeding with the HFD)
  4. bFinal body weight was measured at 13 weeks of age (at 7 weeks of feeding with the HFD)
  5. cSubcutaneous fat was defined as fat pads below the root of the forefoot on one side of the body
  6. NS not significant