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Table 2 Association of haplotypes consisting of three SNPs of ABCB1 with atorvastatin-induced liver injury

From: ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population

rs1128503 rs2032582 rs1045642 Number of carriers P valueb
    AILIa (%) Non-AILIa (%)  
T T T 15 (50.0) 237 (57.2) 0.45
C G C 11 (36.7) 158 (38.2) 1.00
T G C 16 (53.3) 126 (30.4) 0.014
C A C 4 (13.3) 128 (30.9) 0.060
T G T 3 (10.0) 25 (6.0) 0.45
T T C 0 (0.0) 24 (5.8) 0.39
C G T 2 (6.7) 11 (2.7) 0.22
T A C 0 (0.0) 5 (1.2) 1.00
C T T 0 (0.0) 2 (0.5) 1.00
C T C 0 (0.0) 2 (0.5) 1.00
  1. Abbreviation: AILI atorvastatin-induced liver injury
  2. aAILI, N = 30; Non-AILI, N = 414
  3. bThe significant P value after Bonferroni correction is less than 0.005