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Table 3 Population-based comparative analysis on haplotype frequency

From: Monoamine oxidase B gene variants associated with attention deficit hyperactivity disorder in the Indo-Caucasoid population from West Bengal

Groups

Variant combinations

`Haplotypes

Control

Proband

Chi-square (p-value)

Odds Ratio (95 % confidence interval)

Alla

rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440

A-A-C-C-T-C-C

0.04

0

5.27 (0.02)

0.13 (0.03–0.65)

A-A-C-C-T-C-T

0.32

0.49

12.14 (0.0005)

2.08 (1.36–3.19)

A-A-T-C-T-C-C

0.02

0

4.02 (0.04)

0.13 (0.02–0.96)

A-A-T-C-T-C-T

0.03

0

6.07 (0.01)

0.13 (0.03–0.66)

A-G-C-C-T-C-T

0.03

0.09

4.06 (0.04)

2.5 (1.04–6.03)

A-G-T-A-C-T-C

0.07

0.15

4.29 (0.038)

2.21 (1.13–4.32)

A-G-T-C-T-C-T

0.03

0

5.04 (0.02)

0.13 (0.02–0.78)

G-A-C-C-T-C-C

0.03

0

4.03 (0.04)

0.13 (0.02–0.88)

G-A-C-C-T-C-T

0.08

0.18

6.26 (0.01)

2.46 (1.33–4.58)

G-A-T-C-T-C-T

0.02

0

4.02 (0.04)

0.13 (0.02–0.96)

G-G-T-A-T-C-C

0.02

0

4.06 (0.04)

0.13 (0.02–0.91)

G-G-T-A-T-C-T

0.04

0

7.05 (0.008)

0.13 (0.03–0.57)

G-G-T-C-T-C-T

0.02

0

3.01 (0.08)

0.14 (0.01–1.3)

rs2283728-rs3027440

C-C

0.11

0.02

9.43 (0.002)

0.25 (0.11–0.57)

C-T

0.47

0.77

32.72 (1.07e-008)

3.6 (2.34–5.55)

T-C

0.16

0.16

0.07 (0.78)

0.98 (0.55–1.75)

T-T

0.27

0.05

28.27 (1.05e-007)

0.2 (0.12–0.36)

Maleb

rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440

A-A-C-C-T-C-C

0.05

0

6.2 (0.01)

0.13 (0.03–0.65)

A-A-C-C-T-C-T

0.26

0.53

19.98 (7.85e-006)

3.16 (1.2–5.23)

A-A-T-C-T-C-C

0.03

0

4.1 (0.04)

0.13 (0.02–0.94)

A-A-T-C-T-C-T

0.03

0

4.1 (0.04)

0.13 (0.02–0.94)

A-G-T-A-C-T-C

0.04

0.15

8.91 (0.003)

3.58 (1.55–8.3)

A-G-T-A-T-C-T

0.06

0.008

5.71 (0.016)

0.2 (0.05–0.75)

A-G-T-C-T-C-T

0.04

0

5.14 (0.02)

0.13 (0.02–0.76)

G-A-C-C-T-C-C

0.03

0

4.1 (0.04)

0.13 (0.02–0.94)

G-A-C-C-T-C-T

0.06

0.17

7.75 (0.005)

3.04 (1.39–6.66)

G-A-T-C-T-C-T

0.03

0

4.1 (0.04)

0.13 (0.02–0.94)

G-G-T-A-T-C-C

0.03

0

4.1 (0.04)

0.13 (0.02–0.94)

G-G-T-A-T-C-T

0.02

0

3.06 (0.08)

0.13 (0.01–1.28)

G-G-T-C-T-C-T

0.02

0

3.06 (0.08)

0.13 (0.01–1.28)

 

rs56220155-rs2283728-rs3027440

A-C-C

0.13

0.02

11.85 (0.0006)

0.19 (0.07–0.49)

A-C-T

0.33

0.71

35.98 (1.99e-009)

4.52 (2.76–7.42)

A-T-C

0.05

0

6.2 (0.01)

0.13 (0.03–0.65)

A-T-T

0.1

0

12.7 (0.0004)

0.12 (0.04–0.39)

G-C-C

0.02

0

2.03 (0.15)

0.13 (0.008–2.14)

G-C-T

0.06

0.08

0.54 (0.46)

1.45 (0.54–3.86)

G-T-C

0.11

0.16

1.17 (0.28)

1.49 (0.72–3.06)

G-T-T

0.22

0.04

17.54 (2.82e-005)

0.21 (0.1–0.43)

Femalec

rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440

A-G-C-C-T-C-T

0

0.08

3.69 (0.055)

8.23 (1.13–59.77)

G-G-T-A-T-C-T

0.08

0

4.16 (0.04)

0.13 (0.02–0.97)

  1. a N = 125 male and 25 female controls/126 male and 24 female probands
  2. b N = control 125/126 probands
  3. c N = 25 control/24 probands
  4. Statistically significant differences are presented in bold
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BMC Genomic Data

ISSN: 2730-6844

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