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Table 3 Population-based comparative analysis on haplotype frequency

From: Monoamine oxidase B gene variants associated with attention deficit hyperactivity disorder in the Indo-Caucasoid population from West Bengal

Groups Variant combinations `Haplotypes Control Proband Chi-square (p-value) Odds Ratio (95 % confidence interval)
Alla rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440 A-A-C-C-T-C-C 0.04 0 5.27 (0.02) 0.13 (0.03–0.65)
A-A-C-C-T-C-T 0.32 0.49 12.14 (0.0005) 2.08 (1.36–3.19)
A-A-T-C-T-C-C 0.02 0 4.02 (0.04) 0.13 (0.02–0.96)
A-A-T-C-T-C-T 0.03 0 6.07 (0.01) 0.13 (0.03–0.66)
A-G-C-C-T-C-T 0.03 0.09 4.06 (0.04) 2.5 (1.04–6.03)
A-G-T-A-C-T-C 0.07 0.15 4.29 (0.038) 2.21 (1.13–4.32)
A-G-T-C-T-C-T 0.03 0 5.04 (0.02) 0.13 (0.02–0.78)
G-A-C-C-T-C-C 0.03 0 4.03 (0.04) 0.13 (0.02–0.88)
G-A-C-C-T-C-T 0.08 0.18 6.26 (0.01) 2.46 (1.33–4.58)
G-A-T-C-T-C-T 0.02 0 4.02 (0.04) 0.13 (0.02–0.96)
G-G-T-A-T-C-C 0.02 0 4.06 (0.04) 0.13 (0.02–0.91)
G-G-T-A-T-C-T 0.04 0 7.05 (0.008) 0.13 (0.03–0.57)
G-G-T-C-T-C-T 0.02 0 3.01 (0.08) 0.14 (0.01–1.3)
rs2283728-rs3027440 C-C 0.11 0.02 9.43 (0.002) 0.25 (0.11–0.57)
C-T 0.47 0.77 32.72 (1.07e-008) 3.6 (2.34–5.55)
T-C 0.16 0.16 0.07 (0.78) 0.98 (0.55–1.75)
T-T 0.27 0.05 28.27 (1.05e-007) 0.2 (0.12–0.36)
Maleb rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440 A-A-C-C-T-C-C 0.05 0 6.2 (0.01) 0.13 (0.03–0.65)
A-A-C-C-T-C-T 0.26 0.53 19.98 (7.85e-006) 3.16 (1.2–5.23)
A-A-T-C-T-C-C 0.03 0 4.1 (0.04) 0.13 (0.02–0.94)
A-A-T-C-T-C-T 0.03 0 4.1 (0.04) 0.13 (0.02–0.94)
A-G-T-A-C-T-C 0.04 0.15 8.91 (0.003) 3.58 (1.55–8.3)
A-G-T-A-T-C-T 0.06 0.008 5.71 (0.016) 0.2 (0.05–0.75)
A-G-T-C-T-C-T 0.04 0 5.14 (0.02) 0.13 (0.02–0.76)
G-A-C-C-T-C-C 0.03 0 4.1 (0.04) 0.13 (0.02–0.94)
G-A-C-C-T-C-T 0.06 0.17 7.75 (0.005) 3.04 (1.39–6.66)
G-A-T-C-T-C-T 0.03 0 4.1 (0.04) 0.13 (0.02–0.94)
G-G-T-A-T-C-C 0.03 0 4.1 (0.04) 0.13 (0.02–0.94)
G-G-T-A-T-C-T 0.02 0 3.06 (0.08) 0.13 (0.01–1.28)
G-G-T-C-T-C-T 0.02 0 3.06 (0.08) 0.13 (0.01–1.28)
  rs56220155-rs2283728-rs3027440 A-C-C 0.13 0.02 11.85 (0.0006) 0.19 (0.07–0.49)
A-C-T 0.33 0.71 35.98 (1.99e-009) 4.52 (2.76–7.42)
A-T-C 0.05 0 6.2 (0.01) 0.13 (0.03–0.65)
A-T-T 0.1 0 12.7 (0.0004) 0.12 (0.04–0.39)
G-C-C 0.02 0 2.03 (0.15) 0.13 (0.008–2.14)
G-C-T 0.06 0.08 0.54 (0.46) 1.45 (0.54–3.86)
G-T-C 0.11 0.16 1.17 (0.28) 1.49 (0.72–3.06)
G-T-T 0.22 0.04 17.54 (2.82e-005) 0.21 (0.1–0.43)
Femalec rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440 A-G-C-C-T-C-T 0 0.08 3.69 (0.055) 8.23 (1.13–59.77)
G-G-T-A-T-C-T 0.08 0 4.16 (0.04) 0.13 (0.02–0.97)
  1. a N = 125 male and 25 female controls/126 male and 24 female probands
  2. b N = control 125/126 probands
  3. c N = 25 control/24 probands
  4. Statistically significant differences are presented in bold