Consomic mouse strain selection based on effect size measurement, statistical significance testing and integrated behavioral z-scoring: focus on anxiety-related behavior and locomotion

Table 2 List of behavioral variables measured in the mHB and used in this study

MOTIVATIONAL SYSTEM
Behavioral dimension
Variable
ANXIETY-RELATED BEHAVIOR
Avoidance [z] ^a
Total number of board entries (freq)[−z]
Latency until first the board entry (s) [z]
Percentage of time on the board (%) [−z]
Risk assessment [z]
Total number of risk assessments (freq) [z]
Latency until the first risk assessment (s) [−z]
Arousal [z]
Total number of self-groomings (freq) [z]
Latency until first self-grooming (s) [−z]
Percentage of time self-grooming (%) [z]
Total number of defecations (freq) [z]
Latency until first bolus (s) [−z]
Total number of urinations (freq) [z]
Latency until first urination (s) [−z]
LOCOMOTION
Total number of line crossings (freq) [z]
Latency until first line crossing (s) [−z]

^a The directionality of the z-scores was adjusted so that increased score values reflected increased values for that behavioral dimension or motivational system: [z] = regular z-score, [−z] = adjusted z-score

ISSN: 2730-6844