Table 9 Haplotype associations of the eight SNPs in FASN with milk production traits in Chinese Holstein cattle (LSM ± SE)

FASN haplotypes

C10:0

C12:0

C14:0

C14:1

C16:0

C16:1

H1H1(88)

2.02 ± 0.05^a

2.54 ± 0.07^A

9.27 ± 0.12^A

0.78 ± 0.03

32.45 ± 0.33

1.79 ± 0.05

H2H1(103)

2.23 ± 0.05^b

2.81 ± 0.06^B

9.75 ± 0.11^B

0.80 ± 0.03

32.41 ± 0.29

1.72 ± 0.04

H2H2(24)

2.12 ± 0.09^b

2.54 ± 0.12^B

9.53 ± 0.20^AB

0.76 ± 0.06

31.54 ± 0.53

1.79 ± 0.07

H2H3(28)

2.16 ± 0.08^b

2.80 ± 0.10^B

9.95 ± 0.17^B

0.76 ± 0.05

32.90 ± 0.48

1.76 ± 0.07

H3H1(57)

2.09 ± 0.06^b

2.60 ± 0.08^B

9.22 ± 0.14^A

0.77 ± 0.04

31.84 ± 0.37

1.82 ± 0.05

H3H3(10)

2.16 ± 0.13^b

2.72 ± 0.17^B

9.43 ± 0.29^AB

0.74 ± 0.08

32.59 ± 0.77

1.80 ± 0.11

P-value

0.0204

0.0057

0.0001

0.9268

0.2257

0.4522

FASN haplotypes

C18:0

C18:1n9c

C18:2n6c

CLA

C14index

C16index

H1H1(88)

12.69 ± 0.18

29.59 ± 0.24^AC

4.07 ± 0.03

0.38 ± 0.01

7.79 ± 0.26

5.26 ± 0.12

H2H1(103)

12.51 ± 0.16

28.89 ± 0.21^BC

4.04 ± 0.02

0.37 ± 0.01

7.61 ± 0.23

5.03 ± 0.10

H2H2(24)

12.62 ± 0.29

30.56 ± 0.38^A

4.05 ± 0.04

0.37 ± 0.02

7.46 ± 0.42

5.36 ± 0.19

H2H3(28)

12.22 ± 0.26

28.31 ± 0.34^B

4.14 ± 0.04

0.40 ± 0.02

7.16 ± 0.37

5.08 ± 0.17

H3H1(57)

12.65 ± 0.20

29.85 ± 0.27^A

4.11 ± 0.03

0.39 ± 0.01

7.68 ± 0.29

5.45 ± 0.13

H3H3(10)

12.38 ± 0.41

28.91 ± 0.55^ABC

4.03 ± 0.06

0.40 ± 0.03

7.23 ± 0.60

5.25 ± 0.27

P-value

0.6616

<.0001

0.0792

0.4543

0.7264

0.0548

FASN Haplotypes

C18index

SFA

UFA

H1H1(88)

69.95 ± 0.53

61.15 ± 0.32^AB

37.20 ± 0.29^AB

H2H1(103)

69.71 ± 0.47

61.87 ± 0.29^A

36.40 ± 0.26^A

H2H2(24)

70.75 ± 0.86

60.39 ± 0.52^AB

38.15 ± 0.47^B

H2H3(28)

69.85 ± 0.77

62.20 ± 0.46^AB

35.99 ± 0.42^A

H3H1(57)

70.25 ± 0.60

60.69 ± 0.36^B

37.55 ± 0.33^B

H3H3(10)

70.11 ± 1.24

61.75 ± 0.74^AB

36.54 ± 0.68^AB

P-value

0.8619

0.0025

<.0001