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Table 2 Association of the RGS2 rs4606 genotypes with all preeclampsia patients and in groups divided by BMI

From: An RGS2 3′UTR polymorphism is associated with preeclampsia in overweight women

BMI category   na CC GG or CG OR (95 % CI) P
All Preeclampsia 1324 780 (58.9) 544 (41.1) 1.109 (0.919–1.338) 0.282
Control 694 426 (61.4) 268 (38.6)
Normal weight (BMI < 25 kg/m2) Preeclampsia 784 484 (61.7) 300 (38.3) 0.971 (0.769–1.226) 0.806
Control 480 293 (61.0) 187 (39.0)
Overweight (BMI ≥ 25 kg/m2 and < 30 kg/m2) Preeclampsia 310 162 (52.3) 148 (47.7) 1.635 (1.103–2.423) 0.014
Control 159 102 (64.2) 57 (35.8)
Obese (BMI ≥ 30 kg/m2) Preeclampsia 227 133 (58.6) 94 (41.4) 0.913 (0.504–1.655) 0.764
Control 55 31 (56.4) 24 (43.6)
  1. Binary logistic regression: preeclampsia patients vs control subjects, dominant model. Number of subjects and frequencies (%) are presented. OR indicates odds ratio, CI confidence interval and BMI body mass index. aAltogether 1324 preeclamptic and 694 non-preeclamptic women were successfully genotyped. BMI information was missing for 3 preeclamptic cases (1 CC and 2 CG genotypes)