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Fig. 1 | BMC Genetics

Fig. 1

From: Evaluation of forensic DNA mixture evidence: protocol for evaluation, interpretation, and statistical calculations using the combined probability of inclusion

Fig. 1

A depiction of the TPOX locus in an assumed two person mixture. Threshold parameters in this example are: ST = 300 and AT = 50 RFU. If the overall profile supports the best assumption of a two-person mixture, then plausible genotype deconvolution should proceed considering a two-person contribution. The ratio of allele 11:8 is ~7:1. If the contributors donated different amounts to the signal, then plausible genotype deconvolutions to explain the mixture are 8, 8 and 11,11 and 8,11 and 11,11. There is little, if any, possibility of the mixture being derived from an “11,11” and an “8,Q” (where Q stands for an unidentified dropped out allele). Hence, there is no reasonable expectation of allele drop-out, and the locus can be used in the CPI calculation

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