Fig. 2From: Evaluation of forensic DNA mixture evidence: protocol for evaluation, interpretation, and statistical calculations using the combined probability of inclusionA depiction of the blue dye channel of a Globalfiler STR profile in an assumed two person mixture. Threshold parameters in this example are: ST = 300 and AT = 50 RFU. At four out of five loci there are visible peaks below the ST that can be assigned as alleles and therefore these four loci are disqualified (Rule 1). At the vWA locus no peaks are observed below the ST. However, allele drop-out is possible, suggesting that the vWA locus also should be disqualified from use in the CPI calculation (note the use of Rule 3 below may allow re-qualification of the D3S1358 locus). N.B., as emphasized in the protocol described herein, a major contributor could be determined readily across the entire profile and if attempted all loci would be interpretable for that purposeBack to article page